Clinical trials Medicine Science

Pulse oximetry: Racial disparities pop up in unpredictable places

Evidence increasingly suggests that pulse oximetry overestimates the blood oxygenation in Black patients. It’s a problem that’s been discussed a long time that took a pandemic to bring to public consciousness. How can SBM decrease or eliminate such healthcare disparities?

Antivaccine nonsense Bad science Medicine Skepticism/critical thinking

Norman Fenton: “It’s not p-hacking if you don’t use p-values.”

Defending an awful paper on COVID-19 vaccine adverse events, Prof. Norman Fenton claims that it can’t be p-hacking if you don’t use p-values. Hilarity ensues.

Antivaccine nonsense Bad science Clinical trials Medicine

Peter Doshi vs. COVID-19 vaccines, the latest round

BMJ Senior Editor Peter Doshi published a preprint misleadingly “reanalyzing” phase 3 clinical trials to falsely conclude that mRNA vaccines to cause more harm than good. I sense…p-hacking. That, and comparing apples to oranges.

Clinical trials Complementary and alternative medicine Integrative medicine Medicine Pseudoscience Quackery

Is it even possible to design high quality acupuncture trials?

Acupuncture advocates have published guidelines for “rigorous” acupuncture randomized controlled trials. While that sounds good on the surface, the devil is in the details, which reveal that acupuncturists’ dedication to scientific rigor is perhaps not so strong.

Clinical trials Medicine Science Skepticism/critical thinking

Here we go again: Is evidence-based medicine an “illusion”?

Every so few years, someone writes in a reputable journal that evidence-based medicine is corrupt or an “illusion.” Here we go again, this time in The BMJ, and antivaxxers are going wild.

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