Antivaccine nonsense Clinical trials Medicine

How EBM fundamentalism was weaponized against public health in 2023

Evidence-based medicine (EBM) has been a very useful paradigm for assessing evidence in medicine. However, like any other framework, it can be misused, particularly when fundamentalist EBM methodolatry leads to its inappropriate application to questions for which it is ill-suited, a misuse that has been weaponized against public health during the pandemic.

Clinical trials Medicine Skepticism/critical thinking

The Cochrane mask fiasco: Does EBM predispose to COVID contrarianism?

Earlier this month the Cochrane Collaborative was forced to walk back the conclusions of a review by Tom Jefferson et al that had been spun in the media as proving that “masks don’t work.” Tom Jefferson himself has been problematic about vaccines for a long time, but the rot goes deeper. What is it about the evidence-based medicine paradigm that results in misleading conclusions?

Antivaccine nonsense Bad science Clinical trials Medicine

Update: An antivax preprint is now antivax propaganda disguised as a peer-reviewed publication in…Vaccine!

In order portray COVID-19 vaccines as dangerous, Peter Doshi has now managed to get poorly designed and performed “reanalyses” of the clinical trial data used by the FDA to grant emergency use approval of the Pfizer and Moderna vaccines published in two reputable journals, The BMJ and Vaccine? What happened?