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How “natural herd immunity” approaches to the pandemic destroyed public health

Jeffrey Tucker recently bragged that “natural herd immunity” approaches to the pandemic like his Great Barrington Declaration had “changed everything.” Unfortunately, he wasn’t wrong and worse, these changes were not a good thing.

It has been over three years now since the publication of the Great Barrington Declaration (GBD), whose authors in early October 2020 advocated a “natural herd immunity” approach to the pandemic, in which the young and healthy, who were (presumably) at very low risk of serious illness and death from COVID-19, would be allowed to go (mostly) about their business reopening society, while the elderly and those with chronic medical conditions, who were at the highest risk of complications and death from the novel coronavirus, would supposedly be kept safe with “focused protection.” The idea was that, by letting SARS-CoV-2 circulate in the “low risk” population we would reach “natural herd immunity” more rapidly—in six months!—all without the serious damaging consequences of business closures (which proponents of a GBD-like approach always called “lockdowns,” whether they were lockdowns or not) and all the other public health interventions instituted early in the pandemic to slow the spread of the novel coronavirus. Unfortunately, one of the requirements to achieve “natural herd immunity” is that postinfection immunity—which antivaxxers like to refer to as “natural immunity“—be durable, and, as we later learned with the Delta and Omicron waves, a coronavirus that was spreading widely through a population of billions was very capable of evolving into new variants that could not only become a lot more transmissible than the original Wuhan strain but also evade immunity acquired as a result of infection with prior variants. Then there was the problem that the GBD never really defined “focused protection” in a way that could be operationalized. It appeared to mean something akin to indefinite quarantine of the “high risk” their homes, ignoring that these people could never entirely avoid interacting with all those young healthy people spreading the virus. Moreover, in practice “focused protection” could never really have worked, anyway,

So from that consideration alone, “natural herd immunity” was always a pipe dream, but it also turns out that “focused protection” in practice could never really have worked anyway, something that even Gabrielle Bauer of the Brownstone Institute (the “spiritual child of the GBD“) implicitly admitted this year without actually admitting it. There are many good reasons why I referred to the GBD as eugenicist mere days after it was published and continue to do so. It was (and is) eugenicist in that it basically advocated letting the elderly and unhealthy die in service of society. (Seriously, I kept thinking of the term “useless eaters” as I read the declaration.) Unfortunately, the GBD was highly influential in the US, UK, and a number of other countries and remains so to this day, even as GBD proponents, including the Brownstone Institute, have become increasingly antivaccine.

Indeed, what inspired this post were two articles, the first a bit of self-congratulatory wankery published by Jeffrey Tucker entitled The Declaration That Wasn’t Supposed to Happen. Contrast that to an article that had appeared a few days earlier on the website of the John Snow Memorandum, a group of public health professionals that pointed out from the beginning how misguided and dangerous GBD-like “natural herd immunity” approaches to a pandemic are, entitled ‘Endemic’ SARS-CoV-2 and the death of public health. As I like to say, once it had become clear to GBD advocates that “natural herd immunity” was nowhere near, much less just six months away, many of them pivoted to a shoulder shrug about how SARS-CoV-2 would just become “endemic” and that everything would be fine, ignoring all their claims of how the virus would be brought under control through the magic of “natural herd immunity.” I can’t help but contrast the two, particularly in light of a nearly contemporaneous—and completely accurate statement—by Dr. Jerome Adams, Surgeon-General during the Trump Administration, that advocates of a GBD-like approach to the pandemic had wanted to use children as guinea pigs by letting them be infected in order to reach “natural herd immunity” faster. He was basically saying the same thing that I’ve been saying, although, although Dr. Jonathan Howard (who even wrote a book about it) had been saying it all along more frequently and powerfully than I:

Finally figured it out, did ya, Dr. Adams?
If only Dr. Adams had…oh, you know…done something about this when he was in a position to do something… If only…

Sadly, Dr. Adams’ characterization of what happened is quite accurate. So let’s look at the Brownstone Institute’s shiny happy version of history and compare it to reality, shall we?

Great Barrington Declaration authors Martin Kulldorff, Sunetra Gupta, and Jay Bhattacharya
The Great Barrington Declaration authors in front of the American Institute for Economic Research in Great Barrington. Yet they take umbrage when it’s pointed out that the AIER was behind the declaration. (Left to right: Martin Kulldorff, Sunetra Gupta, and Jay Bhattarcharya.)

Jeffrey Tucker’s shiny happy “natural herd immunity,” championed by brave maverick doctors

For those of you who don’t remember, Jeffrey Tucker is the founder of the Brownstone Institute; indeed, it was he himself who, after having founded it in 2021, explicitly called his new institute the “spiritual child of the GBD.” And why not? Tucker was instrumental in creating the GBD. In the summer and fall of 2020, he was the editorial director of the right wing “free market” think tank American Institute for Economic Research, (AIER) whose headquarters in Great Barrington, MA provided the name for the GBD. It was at the AIER headquarters where Tucker, helped by a like-minded Harvard statistician and later GBD signatory named Martin Kulldorff, gathered the other two authors of the Declaration, Stanford health policy professor Jay Bhattacharya and Oxford theoretical epidemiologist Sunetra Gupta, for a press event where the three scientists just so happened to pen the GBD as well. Indeed, not long after the GBD was released, Tucker bragged on a podcast how he had invited Kulldorff to the AIER headquarters, found him so enthusiastic about opposing “lockdowns” that Kulldorff volunteered to gather other like-minded scientists for a “conference” (complete with press) where the GBD ended up being drafted and announced, and then been in the “room where it happened” (apologies to Lin-Manuel Miranda) as the GBD was being discussed and written. Basically, Tucker was the dark far-right wing ideologue who recruited Kulldorff as a useful idiot for his cause, and Kulldorff did not disappoint.

As such, Tucker remains very proud of his creation, as he brags in The Declaration That Wasn’t Supposed to Happen:

It’s been a continuing mystery for three years, at least to me but many others too. In October 2020, in the midst of a genuine crisis, three scientists made a very short statement of highly public health wisdom, a summary of what everyone in the profession, apart from a few oddballs, believed only a year earlier. The astonishing frenzy of denunciation following that document’s release was on a level I’ve never seen before, reaching to the highest levels of government and flowing through the whole of media and tech. It was mind-boggling.

And:

That was the period of the grant amnesia. The conventional wisdom turned on a dime toward full backing of regime priorities, a shift more extreme and mind boggling that anything in dystopian fiction.

This is some very seriously amnestic revisionist history. While it is true that the GBD was denounced by public health officials for the unworkable ideological (and eugenicist) example of “magnified minority” that it clearly was, such denunciations were nothing compared to the embrace of GBD-like policies by, for example, the Trump administration in the US and the Boris Johnson administration in the UK, as well as a number of state governments. Indeed, as Gavin Yamey and I noted in 2021:

In October 2020, Gupta, Kulldorff, and Bhattacharya met with two of US President Donald Trump’s senior health officials, Health and Human Services Secretary Alex Azar and Scott Atlas. Atlas was at the time on leave from his fellowship at the Hoover Institution, a conservative think tank affiliated with Stanford University. The meeting reportedly led the administration to eagerly embrace the GBD. Nor did the GBD authors limit their efforts to national governments. For example, in March 2021 Florida Governor Ron DeSantis hosted a video roundtable with Atlas, Gupta, Kulldorff, and Bhattacharya, where they expressed opposition to masks, testing and tracing, physical distancing, and mass vaccination. YouTube removed the video “because it included content that contradicts the consensus of local and global health authorities regarding the efficacy of masks to prevent the spread of Covid-19.” GBD authors, predictably, cried, “Censorship!” Bhattacharya continues to advise Governor DeSantis on Florida’s covid-19 policies, including providing legal testimony in support of DeSantis’s ban on mask mandates in public schools.

That’s not even counting how Kulldorff, Bhattacharya, and other advocates of “natural herd immunity”—e.g., Dr. Joseph Ladapo, who is now Florida’s Surgeon-General—had met with Donald Trump himself the previous summer:

Hey, wait a minute. Did John Snow Memorandum members ever get to meet with President Trump?

Far from being the poor persecuted, “silenced,” and “cancelled” brave mavericks, GBD advocates were courted at the highest levels of government. While it is true that this courtship ceased when President Joe Biden was inaugurated in January 2021, they had had months of access to the highest levels of government before and after the GBD was announced.

Unsurprisingly, Tucker tries to paint the GBD as being entirely reasonable. Unfortunately, he has to engage in a bit of more misdirection to do it:

For proof that nothing in the document was particularly radical, look no further than the March 2, 2020, letter from Yale University signed by 800 top professionals. It warned against quarantines, lockdowns, closures, and travel restrictions. It said such extreme measures “can undermine public trust, have large societal costs and, importantly, disproportionately affect the most vulnerable segments in our communities.” That document appeared only two weeks before the lockdowns announced by the Trump administration.

Let’s take a look at what the letter from Yale University actually said, shall we, as opposed to what Tucker claims that it said in his link above, which emphasized issues of social and economic justice in any pandemic response, including sufficient government funding to support people and businesses affected by pandemic mitigations; prioritizing voluntary over mandatory interventions (the only part that sort of overlaps with Brownstone and the GBD but where the comparison leaves out a lot of context, such as the part where it is demanded that people subject to mandatory quarantine or “lockdown” receive adequate financial support to minimize “job loss, economic hardship, and undue burden”); and noting that the “effectiveness of regional lockdowns and travel bans depends on many variables, and also decreases in the later stages of an outbreak,” a clear swipe at the Trump administration’s early institution of poorly thought-out travel bans in early 2020.

Enter the brave maverick of AIER and the GBD:

Seven months later, the Great Barrington Declaration said something very similar to the Yale document. It was a summary statement concerning what governments and society should and should not do during pandemics. They should seek to allow everyone to live as normally as possible in order to avoid guaranteed damage from coerced disruptions. And the vulnerable population – those who would experience medically significant impacts from exposure – should be protected from exposure insofar as doing so is consistent with human rights and choice. It was nothing particularly novel, much less radical. Indeed, it was accepted wisdom the year before and for the previous century. The difference this time, however, is that the statement was released during the wildest and most destructive science experiment in modern times. The existing policy of lockdowns was utter wreckage: of businesses, schools, churches, civic life, and freedom itself. Masks were being forced on the whole population, including children. Governments were attempting a regime of test, track, trace, and isolate, as if there were ever any hope of containing a respiratory pathogen with a zoonotic reservoir.

“Zoonotic reservoir”? I laughed out loud reading that part, given how much Brownstone and Tucker have gone all-in with “lab leak” conspiracy theories. I can only guess that Tucker included that last part as a means of seeming reasonable.

In any event, once again, this is revisionist history and bad science. Those of us around and paying attention in October 2020 immediately recognized the GBD for what it was, a propaganda document, a technique of “magnified minority” like that previously used by creationists, climate science deniers, and HIV/AIDs deniers, designed to make it appear that a fringe scientific viewpoint has a lot of support in the scientific community. (I will repeat that the GBD was also eugenicist.) Again, it was a proposal that on a very practical basis couldn’t have worked because it never defined “focused protection” adequately and the measures needed to make focused protection work would have required something resembling “lockdowns” anyway, leaving aside, again, the requirement for durable postinfection immunity for “natural herd immunity” to be achievable. That’s just one reason why I was so amused when Brownstone flack Gabrielle Bauer admitted that the GBD “didn’t get every detail right,” one of those minor details being that “neither infection nor vaccination provides durable immunity against Covid, leaving people vulnerable to second (and fifth) infections,” you know, the single most important requirement for “natural herd immunity” being durable postinfection immunity. Of course, these days, Brownstone has a two year history of parroting antivax tropes like fantasizing about a “Nuremberg 2.0” in which “lockdowners” and supporters of vaccine mandates and other public health interventions will be called to account for their “crimes”; likening public health interventions to slow the spread of COVID-19 to slavery, religion, or a Communist dictatorship; or just plain spreading pure, unadulterated antivax misinformation.

Conveniently enough, in his narrative of “censorship” and “persecution” Tucker goes right there:

Reading those words today, in light of what we now know, we can start to make sense of the sheer panic at the top. Natural infection and immunity? Can’t talk about that. The end of the pandemic is not “dependent upon” the vaccine? Can’t say that either. Go back to normal for all populations without significant medical risk? Unsayable. You need only reflect on the astounding barrage of vaccine propaganda that began immediately upon release, the attempt to mandate it on the whole population and now the addition of the Covid jab to the childhood schedule even though children are of near zero risk. This is all about product sales, as you can easily discern from the unrelenting ad videos made by the new head of the CDC. As for the product effectiveness itself, there seems to be no end to the ensuing problems. It was not a sterilizing inoculation, and it appears that the manufacturers always knew that. It could not stop infection or transmission. The hazards associated with it were also known early on. Every day, the news gets more grim: in the latest revelation, the CDC seems to have kept two separate books on vaccine injury, one public (showing harms without precedent but which has been deprecated by officials) and one yet to be released. Even now, therefore, there is every effort being made to keep a lid on what surely ranks as the greatest failure/scandal in the modern history of public health. Some brave experts called it out before the whole calamity unfolded even further. The problem with the Great Barrington Declaration was not that it was not true. It’s that – unbeknownst to its authors – it flew in the face of one of the most funded and elaborate industrial plots in the history of governance. Just a few sentences sneaking through the wall of censorship they were carefully constructing was enough to threaten and eventually dismantle the best laid plans.

Spare me, Mr. Tucker. In actuality, it was those trying to counter the GBD narrative, which was being promoted by far more than just a right wing think tank and three contrarian scientists, who were the ones drowned out by misinformation. Tucker and the Brownstone Institute can portray themselves as persecuted truth telling heroes all they want, but in reality they represented interests who saw pandemic mitigations as a threat to their ideology and profits.

Which brings us to the depressing article published at the John Snow Memorandum, ‘Endemic’ SARS-CoV-2 and the death of public health.

The downward trajectory of public health since the pandemic

Regular readers might recall that the John Snow Memorandum was a document released by public health scientists in response to the Great Barrington Declaration. John Snow, of course, is considered one of the founders and pioneers of epidemiology, having been the 19th century physician who identified the source of a cholera outbreak in London’s Soho, a particular public water pump. The John Snow Memorandum noted, correctly:

Any pandemic management strategy relying upon immunity from natural infections for COVID-19 is flawed. Uncontrolled transmission in younger people risks significant morbidity(3) and mortality across the whole population. In addition to the human cost, this would impact the workforce as a whole and overwhelm the ability of healthcare systems to provide acute and routine care. Furthermore, there is no evidence for lasting protective immunity to SARS-CoV-2 following natural infection(4) and the endemic transmission that would be the consequence of waning immunity would present a risk to vulnerable populations for the indefinite future. Such a strategy would not end the COVID-19 pandemic but result in recurrent epidemics, as was the case with numerous infectious diseases before the advent of vaccination. It would also place an unacceptable burden on the economy and healthcare workers, many of whom have died from COVID-19 or experienced trauma as a result of having to practise disaster medicine. Additionally, we still do not understand who might suffer from long COVID(3). Defining who is vulnerable is complex, but even if we consider those at risk of severe illness, the proportion of vulnerable people constitute as much as 30% of the population in some regions(8). Prolonged isolation of large swathes of the population is practically impossible and highly unethical. Empirical evidence from many countries shows that it is not feasible to restrict uncontrolled outbreaks to particular sections of society. Such an approach also risks further exacerbating the socioeconomic inequities and structural discriminations already laid bare by the pandemic. Special efforts to protect the most vulnerable are essential but must go hand-in-hand with multi-pronged population-level strategies.

All of which was reasonable and remains reasonable, unlike the “let ‘er rip” approach championed by the GBD, which, contrary to the claims of Tucker and his fellow “natural herd immunity” advocates, was not just “reasonable” and standard public health science. Indeed, this article argues just that, laments what has happened to public health, and expresses fear for the future the next time a new pathogen emerges.

The John Snow Project begins by noting, depressingly:

SARS-CoV-2 is now circulating out of control worldwide. The only major limitation on transmission is the immune environment the virus faces. The disease it causes, COVID-19, is now a risk faced by most people as part of daily life. While some are better than others, no national or regional government is making serious efforts towards infection prevention and control, and it seems likely this laissez-faire policy will continue for the foreseeable future. The social, political, and economic movements that worked to achieve this mass infection environment can rejoice at their success. Those schooled in public health, immunology or working on the front line of healthcare provision know we face an uncertain future, and are aware the implications of recent events stretch far beyond SARS-CoV-2. The shifts that have taken place in attitudes and public health policy will likely damage a key pillar that forms the basis of modern civilized society, one that was built over the last two centuries; the expectation of a largely uninterrupted upwards trajectory of ever-improving health and quality of life, largely driven by the reduction and elimination of infectious diseases that plagued humankind for thousands of years. In the last three years, that trajectory has reversed.

It’s definitely hard to argue with this depressing characterization of the state of public health today. There is now little or no effort in the US or elsewhere in infection control and prevention; it is the ultimate success of disease mongers like Jeffrey Tucker and the Brownstone Institute, along with all the other ideological forces and organizations promoting the same message and politics, that any public health interventions are an unacceptable assault on personal “freedom” that must be resisted at all costs. “We want them infected,” indeed.

The authors go on to provide a brief history of public health, noting key developments that led to its upward trajectory over the last few centuries. These include germ theory, John Snow’s identification of the source of the 1854 London cholera outbreak, vaccination, recognition of the importance of workplace environments and ventilation, and other developments. These trends continued into the 20th century, and a number of diseases were brought under much better control, including diphtheria, pertussis, hepatitis B, polio, measles, mumps, rubella, etc., because of effective vaccination, while diseases like malaria, typhus, typhoid, leprosy, cholera, tuberculosis, and many others, although not eradicated, faded from prominence because they were under better control, at least in industrialized temperate countries.

All of this history led to a recognition:

Furthermore, the idea that infectious diseases should not just be reduced, but permanently eliminated altogether began to be put into practice in the second half of the 20th century3-5 on a global level, and much earlier locally. These programs were based on the obvious consideration that if an infectious agent is driven to extinction, the incalculable damage to people’s health and the overall economy by a persisting and indefinite disease burden will also be eliminated.

Basically, the eradication of some diseases became possible and was even within sight, after the successful eradication of smallpox, with the John Snow Project noting ruefully:

When the COVID-19 pandemic started, global eradication programs were very close to succeeding for two other diseases – polio11,12 and dracunculiasis13. Eradication is also globally pursued for other diseases, such as yaws14,15, and regionally for many others, e.g. lymphatic filariasis16,17, onchocerciasis18,19, measles and rubella20-30. The most challenging diseases are those that have an external reservoir outside the human population, especially if they are insect borne, and in particular those carried by mosquitos. Malaria is the primary example, but despite these difficulties, eradication of malaria has been a long-standing global public health goal31-33 and elimination has been achieved in temperate regions of the globe34,35, even though it involved the ecologically destructive widespread application of polluting chemical pesticides36,37 to reduce the populations of the vectors. Elimination is also a public goal for other insect borne diseases such as trypanosomiasis38,39.

Noting that, because of zoonotic reservoirs of a number of diseases, this principle in dealing with emerging infectious diseases became paramount:

Because it is much easier to stop an outbreak when it is still in its early stages of spreading through the population than to eradicate an endemic pathogen, the governing principle has been that no emerging infectious disease should be allowed to become endemic. This goal has been pursued reasonably successfully and without controversy for many decades. The most famous newly emerging pathogens were the filoviruses (Ebola44-46, Marburg47,48), the SARS and MERS coronaviruses, and paramyxoviruses like Nipah49,50. These gained fame because of their high lethality and potential for human-to-human spread, but they were merely the most notable of many examples. Such epidemics were almost always aggressively suppressed. Usually, these were small outbreaks, and because highly pathogenic viruses such as Ebola cause very serious sickness in practically all infected people, finding and isolating the contagious individuals is a manageable task. The largest such epidemic was the 2013-16 Ebola outbreak in West Africa, when a filovirus spread widely in major urban centers for the first time. Containment required a wartime-level mobilization, but that was nevertheless achieved, even though there were nearly 30,000 infections and more than 11,000 deaths51. SARS was also contained and eradicated from the human population back in 2003-04, and the same happened every time MERS made the jump from camels to humans, as well as when there were Nipah outbreaks in Asia.

Again, it makes perfect senses that it is easier to eliminate a new pathogen before it becomes endemic. Note that I said “easier,” not “easy.” As the example of SARS demonstrates, eliminating such a pathogen before it spreads to become pandemic is nowhere near easy. It takes a lot of resources and effort, as well as a public health infrastructure to implement containment measures. The authors also note that HIV/AIDS could not be contained because (1) it integrates into the host genome, making it nearly impossible to eliminate completely and (2) it had made the jump to humans decades before its discovery and recognition, “long before the molecular tools that could have detected and potentially fully contained it existed.” The authors further note that the threat of the emergence of a new pathogen like SARS-CoV-2 had been known and planned for a long time before SARS-CoV-2 actually did emerge, adding that its appearance “should therefore not have been a huge surprise, and should have been met with a full mobilization of the technical tools and fundamental public health principles developed over the previous decades.”

Unfortunately, that actually did not happen, except fitfully, leading the authors to lament the  resulting “death of public health and the end of epidemiological comfort,” which brings the authors to a message very much like that of Dr. Adams, Dr. Howard, myself, and many others, namely that containment was actively sabotaged:

After HIV, SARS-CoV-2 is now the second most dangerous infectious disease agent that is ‘endemic’ to the human population on a global scale. And yet not only was it allowed to become endemic, but mass infection was outright encouraged, including by official public health bodies in numerous countries81-83. The implications of what has just happened have been missed by most, so let’s spell them out explicitly. We need to be clear why containment of SARS-CoV-2 was actively sabotaged and eventually abandoned. It has absolutely nothing to do with the “impossibility” of achieving it. In fact, the technical problem of containing even a stealthily spreading virus such as SARS-CoV-2 is fully solved, and that solution was successfully applied in practice for years during the pandemic.

“Endemic,” of course, means that the virus is just out there and with us, uncontainable because, well, it’s everywhere, despite examples of nations that did successfully contain many COVID-19 outbreaks before abandoning the effort, including Australia, New Zealand, Singapore, Taiwan, Vietnam, Thailand, Bhutan, Cuba, and China, the last of which, according to the John Snow Project, had “successfully contained hundreds of separate outbreaks, before finally giving up in late 2022.”

Contrary to what GBD proponents will tell you, it’s not as though the tools to contain outbreaks of respiratory diseases haven’t been known for decades:

The algorithm for containment is well established – passively break transmission chains through the implementation of nonpharmaceutical interventions (NPIs) such as limiting human contacts, high quality respirator masks, indoor air filtration and ventilation, and others, while aggressively hunting down active remaining transmission chains through traditional contact tracing and isolation methods combined with the powerful new tool of population-scale testing.

They note that using nonpharmaceutical interventions (NPIs_ to break transmission chains and driving the effective reproduction number (Re) to well below 1.0 and keep it there would have been much easier when Re was around 1.3 than it is with Re around 3.0, at least before a new variant emerges to bypass immunity, noting that it was not a technical failure, but rather a failure of will:

This is not a technical problem, but one of political and social will. As long as leadership misunderstands or pretends to misunderstand the link between increased mortality, morbidity and poorer economic performance and the free transmission of SARS-CoV-2, the impetus will be lacking to take the necessary steps to contain this damaging virus.

Moreover, as we have noted all along, starting when the GBD was first declared, powerful political and economic interests aligned to oppose measures necessary to contain the emerging outbreak of SARS-CoV-2 before it got out of control. Gavin Yamey and I wrote about them two years ago, and the John Snow Project reiterates our point now:

Political will is in short supply because powerful economic and corporate interests have been pushing policymakers to let the virus spread largely unchecked through the population since the very beginning of the pandemic. The reasons are simple. First, NPIs hurt general economic activity, even if only in the short term, resulting in losses on balance sheets. Second, large-scale containment efforts of the kind we only saw briefly in the first few months of the pandemic require substantial governmental support for all the people who need to pause their economic activity for the duration of effort. Such an effort also requires large-scale financial investment in, for example, contact tracing and mass testing infrastructure and providing high-quality masks. In an era dominated by laissez-faire economic dogma, this level of state investment and organization would have set too many unacceptable precedents, so in many jurisdictions it was fiercely resisted, regardless of the consequences for humanity and the economy. None of these social and economic predicaments have been resolved. The unofficial alliance between big business and dangerous pathogens that was forged in early 2020 has emerged victorious and greatly strengthened from its battle against public health, and is poised to steamroll whatever meager opposition remains for the remainder of this, and future pandemics.

Notice how much different this reality-based view is compared to the narrative promoted by Jeffrey Tucker. The one thing that I don’t like to have to admit is that Tucker is correct when he says that the GBD won. Where we differ is that, unlike Tucker, I do not view this victory as a good thing. Quite the contrary. Neither do the authors behind the John Snow Memorandum, who sadly note:

The long-established principles governing how we respond to new infectious diseases have now completely changed – the precedent has been established that dangerous emerging pathogens will no longer be contained, but instead permitted to ‘ease’ into widespread circulation. The intent to “let it rip” in the future is now being openly communicated84. With this change in policy comes uncertainty about acceptable lethality. Just how bad will an infectious disease have to be to convince any government to mobilize a meaningful global public health response?

I would go even further. I would argue that eugenics has basically won out over public health. Because SARS-CoV-2 killed mainly—although far from exclusively—the elderly and those with chronic illnesses, views aligning with that of antivaccine crank Del Bigtree, in June 2020 encouraged his followers to “catch this cold” in order to help achieve “natural herd immunity.” The unspoken subtext that reveals the eugenicist intent—usually denied and maybe even not acknowledged, but there nonetheless—is how Bigtree also ranted about those most at risk of COVID-19 having made themselves that way by engaging in high risk behaviors that led to chronic disease, such as drinking and smoking to excess and overeating. (Obesity is a major risk factor for severe disease and death from COVID-19.) Of course, the one risk factor for severe disease and death from COVID-19 that no one has any control over is how old we were when the pandemic hit, given that the risk of severe disease and death climbs sharply with age. I like to point out that, as much as GBD proponents claim that “focused protection” would keep the elderly safe, it couldn’t, can’t, and won’t, because unless you quarantine all the elderly indefinitely they will have interaction with the “low risk” younger people out there necessary to help take care of them. One only has to look at the debacles that occurred in nursing homes early in the pandemic to appreciate how “focused protection” was always a pipe dream, a concession tacked onto the eugenicist vision of the GBD to make it seem less eugenicist.

If you think I’m going too far, just look back a bit. Do you remember how often COVID-19 minimizers would justify doing less (or nothing) to stop the spread of disease because it “only kills the elderly”? I do, and such rhetoric came not just from bonkers antivaxxers like Del Bigtree, either. Do you remember the arguments against vaccinating children against COVID-19 because it “only” kills a few hundred of them a year? I do. Never mind that, on a yearly basis, COVID-19 kills about as many children as the measles did before the vaccine was licensed 60 years ago, adjusted for population? It’s a leading cause of death among children now. “Bioethics”-based arguments not to vaccinate children against COVID-19 are the same old antivax arguments against vaccinating children, just recycled for a new virus, with “esteemed” doctors telling us that we need to accept children dying of COVID-19 “as a matter of course.”

The John Snow Project speculates about how much deadlier COVID-19 would have to become in order to spur the political and social will to actually do something to try to contain it again and come to a depressing conclusion that, even more depressingly, I have a hard time arguing with, namely that, based on the death toll during the Delta and Omicron waves, “12–15,000 dead a day is now a threshold that will not force the implementation of serious NPIs for the next problematic COVID-19 serotype.” They’re not wrong. Over 1 million Americans died during COVID-19, a number that would have been unthinkable in 2019 but now only inspires a collective shrug. That is why the authors, also correctly unfortunately, state that there “can be no doubt, from a public health perspective, we are regressing.” Of that, there is no doubt.

Perhaps the most depressing—yes, even more depressing than the above observations—part of the whole article is how the John Snow Project relates the regression in public health science with respect to infectious disease to all of public health, including vaccines:

We can also expect previously forgotten diseases to return where they have successfully been locally eradicated. We have to always remember that the diseases that we now control with universal childhood vaccinations have not been globally eradicated – they have disappeared from our lives because vaccination rates are high enough to maintain society as a whole above the disease elimination threshold, but were vaccination rates to slip, those diseases, such as measles, will return with a vengeance.

We are, of course, already seeing this, with antivaxxers rejoicing over declines in childhood vaccination rates provoked by the antivaccine sentiment provoked by COVID-19 vaccination mandates. Particularly relevant to what Dr. Adams and Dr. Howard said about the push to reopen schools and let the kids be infected:

Infection, rather than vaccination, was the preferred route for many in public health in 2020, and still is in 2023, despite all that is known about this virus’s propensity to cause damage to all internal organs, the immune system, and the brain, and the unknowns of postinfectious sequelae. This is especially egregious in infants, whose naive immune status may be one of the reasons they have a relatively high hospitalization rate. Some commentators seek to justify the lack of protection for the elderly and vulnerable on a cost basis. We wonder what rationale can justify a lack of protection for newborns and infants, particularly in a healthcare setting, when experience of other viruses tells us children have better outcomes the later they are exposed to disease100? If we are not prepared to protect children against a highly virulent SARS virus, why should we protect against others? We should expect a shift in public health attitudes, since ‘endemicity’ means there is no reason to see SARS-CoV-2 as something unique and exceptional.

Note what I said above about how much the antivax ethos that children don’t need to be vaccinated because COVID-19 supposedly doesn’t kill that many of them has infected the discourse about whether or not children should be vaccinated against the disease. What we are seeing is the same “shoulders shrug” attitude that antivaxxers encouraged before the pandemic, when they would point to episodes of The Brady Bunch and The Flintstones from the 1960s or an episode of The Donna Reed Show from the 1950s, old sitcoms in which measles was played for laughs and treated as something that nearly all children inevitably had to endure, in other words, no big deal. This same attitude has now become common, if not dominant, about COVID-19, stoked by the likes of Tucker and the antivaccine movement. It is the same attitude that antivax doctors like Bog Sears promoted in 2015 and before about measles and other vaccine-preventable childhood diseases.

Unfortunately, as the John Snow Project argues, this lack of concern for mitigating the spread of infectious disease is likely to metastasize to other areas of public health, including worker safety or preventing nosocomial infections in healthcare facilities. After all, earlier this year mask mandates fell in hospitals, even cancer centers:

Worse, we have now entered the phase of abandoning respiratory precautions even in hospitals. The natural consequence of unmasked staff and patients, even those known to be SARS-CoV-2 positive, freely mixing in overcrowded hospitals is the rampant spread of hospital-acquired infections, often among some of the most vulnerable demographics. This was previously thought to be a bad thing. And what of the future? If nobody is taking any measures to stop one particular highly dangerous nosocomial infection, why would anyone care about all the others, which are often no easier to prevent? And if standards of care have slipped to such a low point with respect to COVID-19, why would anyone bother providing the best care possible for other conditions? This is a one-way feed-forward healthcare system degradation that will only continue.

The stress caused by the pandemic has indeed already induced major damage to our healthcare system, damage that is unlikely to be reversed during whatever years remain in my surgical career. What bothers me the most is that I find it difficult to say that the John Snow Project is wrong in its dire predictions. If anything, they might be overly optimistic.

By Orac

Orac is the nom de blog of a humble surgeon/scientist who has an ego just big enough to delude himself that someone, somewhere might actually give a rodent's posterior about his copious verbal meanderings, but just barely small enough to admit to himself that few probably will. That surgeon is otherwise known as David Gorski.

That this particular surgeon has chosen his nom de blog based on a rather cranky and arrogant computer shaped like a clear box of blinking lights that he originally encountered when he became a fan of a 35 year old British SF television show whose special effects were renowned for their BBC/Doctor Who-style low budget look, but whose stories nonetheless resulted in some of the best, most innovative science fiction ever televised, should tell you nearly all that you need to know about Orac. (That, and the length of the preceding sentence.)

DISCLAIMER:: The various written meanderings here are the opinions of Orac and Orac alone, written on his own time. They should never be construed as representing the opinions of any other person or entity, especially Orac's cancer center, department of surgery, medical school, or university. Also note that Orac is nonpartisan; he is more than willing to criticize the statements of anyone, regardless of of political leanings, if that anyone advocates pseudoscience or quackery. Finally, medical commentary is not to be construed in any way as medical advice.

To contact Orac: [email protected]

45 replies on “How “natural herd immunity” approaches to the pandemic destroyed public health”

Orac, give it up already. The level of intellectual dishonesty you assert calls into question who/what you represent, and why. But, that’s besides the point.

Your post is the definitive example of a straw man argument. The straw man is GBD. It’s a straw man because of the massive, obvious elephant in the room, and laughably obvious hole in your premise about GBD….you have zero proof ..ZERO … to prove….even infer….that the non-GBD policies foisted on the public to manage COVID worked. We have copious proof of the disaster of those policies….the social/developmental/scholastic implications on locked down children; the disasterous financial results on the economy….which the same geniuses who locked down the economy decided printing a tillion of new debt was a good way to fix the economic destruction wrought by the “non GBD” approach. The inflation we now face was directly caused by the disasterous , unnecessary lockdown policy. How about the destruction of once great cities like New York and San Fran, thanks to the lock downs.

Despite these self evident and obvious facts about the fruits of the “non GBD” approach….you offer not one iota of proof as to how the “non GBD” approach worked….let alone was better than the “GBD” approach. Basically the idea of your assertion is, as was the case with the incompetents in charge , “I’m the expert, so shut up”. I challenge you Orac….show one study….anything….that proves or even highly suggests that the “non GBD” approach “worked” as in changed the trajectory of the COVID virus. Put a link out for such proof….double dog dare you. You won’t, because you can’t. Hence why, as a perfect leftist tactic, you employ derogatory labels to describe the wrong thinkers…notably “eugenicists” ….of course, you can’t show any proof the “non GBD” approach did anything good, so, of course, make the other side look abhorrent.

The most hillarious aspect of your post is your lament about the impact on public health….for you to wallow in the BS you wallow in, shows you lack even a smidgen of self awareness. You are 100% right that one of the worst casualties of the pandemic is the credibility of public health institutions.

But that lack of credibility is well earned….since public health “experts”, like you, refuse to admit to the incredible destruction caused by your “expert opines”…and, the fact “experts”, like you, lack proof of just about anything, yet you remain disturbingly self righteous. Maybe the fact COVID rapidly morphed into nothing more than a cold for just about everyone, yet “experts” like you insisted on pointless, destructive measures for months has something to do with why the public doesn’t trust public health “experts” (like you).

All that said, I am not asserting the GBD approach was “good” or “bad”. My point is, you got nothing in terms of data to prove the approach unleashed on the US did anything beneficial.

I remember thinking a few years ago when some of the anti-vaxxers were touting it that “natural herd immunity “ was what we had for most childhood diseases back in the 50s. And it never lasted even though the viruses like measles and varicella or bacteria like pertussis were relatively stable.

With something mutating like a coronavirus, it would be hopeless.

You’re welcome to present evidence to support your claim, but you didn’t. I did NOT use the word worthless, but I did use the word hopeless to describe the likelihood of controlling an infectious coronavirus with infection acquired, i.e., natural, immunity.

In general the evidence I have seen shows that both forms of immunity are roughly equivalent in protecting against Covid-19. But acquiring natural immunity involves a cost in deaths, people suffering long Covid-19 and likely future effects, especially to the cardiovascular system. And it’s much easier and safer to give the antibodies a boost or tailor some of them to a new variant with another vaccine shot.

Nevertheless, the accumulating protection from both forms has obviously saved many lives.

The first winter (Jan 21) produced 5.6 million cases and 91,000 deaths for a CFR of 1.6%. That was with practically no vaccinations and an estimated 17% previously infected. The second winter (Jan 22) started with 73% with at least one vaccine dose and about 45% previously infected. Despite three times as many cases (18.4 million), only 58 thousand died for a CFR of 0.3%.

I think reducing the fatality rate by a factor of 5 is far from “worthless”.

And studies of people who were not previously infected showed that the Omicron variant was roughly as dangerous as the previous variants. The supposed mildness of that variant was really due to so many people having some immunity!

Anti-vaxxers love to say herd immunity doesn’t exist and blame it on the vaccines whilst they drive up non-vaccination rates to destroy herd immunity and bring outbreaks back. Kinda like turning a flamethrower on a house and when it catches fire complaining that there’s no way to make a house fireproof.

Wow….What an astonishingly collection of words! It’s truly amazing that someone would actually take the time to create such a collection of words!
Sad, but amazing-:)

nope.

Several countries had severe outcomes. Most were unable to count correctly (due to poor public health systems and / or disincentives, since it’s embarrassing to governments). The president of Tanzania was a Covid denier and then died of Covid, his successor was more reality based.

https://www.economist.com/graphic-detail/coronavirus-excess-deaths-estimates

is the best estimates available for actual death counts, country by country

official deaths for all of Africa – about a quarter million
The Economist estimates actual deaths were at least 1.7 million and could have been five million. The Economist isn’t my politics but they’re serious reporters and their methodology seems accurate.

Algeria, Libya, Egypt, Nigeria, Ethiopia, DRC, South Africa … these and other African countries were especially hard hit.

<

blockquote>
official deaths for all of Africa – about a quarter million
The Economist estimates…>

Funny how in Africa when the bodies are piling up from malaria or famine there are actual counts and the cameras are over them; when it’s from COVID though, we are dealing with estimates.

Only if one believes that official government figures for covid deaths were accurate in most African countries … (or most countries, anywhere). I thought anti-vaxxers thought you couldn’t believe anything governments say?

@ Mark Robinowitz
No you can only not trust official government figures if they are not in line with what people like Igor or Fred.

b.t.w. African countries often have a young population, which may also influence the death count from covid.

The unofficial alliance between big business and dangerous pathogens that was forged in early 2020 has emerged victorious and greatly strengthened from its battle against public health, and is poised to steamroll whatever meager opposition remains for the remainder of this, and future pandemics.

When I saw this opposition to public health by big business strictly to preserve profits I initially thought “well, at least big business doesn’t care so much about whether kids have to stay home from school during outbreaks of dangerous pathogens because they are not losing workers.” But, of course, Jeffrey Tucker shows what an absolute lover of child slavery he is with his 2017 piece “Let the Kids Work” where he gets all excited about grade-school-aged children working in coal mines. ( https://medium.com/fee-org/let-the-kids-work-jeffrey-a-tucker-c8f7ba9d2cb3 ).

I remain convinced that a large part of the motivation for the GBD was because vaccines were just about to come out. They figured the vaccines would stop the disease and they could get on the gravy train for life saying that the lockdowns, etc. were unnecessary. But it turned out that neither the vaccine nor infection produced permanent immunity, so they’ve been scrambling ever since to rewrite history.

Quite possibly, although in early October 2020 there was no way of knowing whether safe and effective vaccines were a couple of months off (as it turned out) or a year off (if the clinical trials had failed to show adequate efficacy and safety). Of course, you do hit on the most important reason why the GBD could never have worked, namely that “natural herd immunity” requires postinfection immunity that is, if not lifelong, at least very long-lasting. We now know that postinfection immunity for COVID-19 is not very long lasting at all, at least not compared to, for example, measles and other diseases that do not mutate as rapidly; so any sort of GBD approach, besides bringing mass death, would never have achieved any real “natural herd immunity

The comparison of COVID or any other RNA virus to measles or Diphtheeria is specious. A measles vaccination gives long term, multi year if not lifetime protection. There is a 50% reduction in antibody levels within 5 months from a COVID Jab. Actual infection with COVID gives comparable antibody levels for 12-13 months, so protection is indeed better, if still transient with infection. But T cell immunity seems to be far better from infection than vaccination. Also, the significant rise in Pericarditis, or even myocarditis post vaccination seems to be a very reel risk in young males especially.
Sweden did not shut down their economy or schools for long periods once they started seeing the actual science from the infections and their looser approach did not negatively impact their result and Florida here in the USA did fine with their loss restrictive approach.
What has killed public trust in the Public Health Mavins were the lies and distortions promulgated by those in positions of official public trust. The CDC, hid data that did not support the official line, government conspired with Big Pharma and Big tech to suppress every true comment that disagreed with government lies. So yes, as a physician and a citizen, I no longer have faith in the CDC, FDA, or any other public health authority that has lied so blatantly and loudly for so long.

J. N. Mixon MD

The shopping cart on the upper right side of his website is just precious. Plus a clue to avoid his practice completely.

Most of the mentions of measles were from the John Snow Project. Orac’s mention of measles was “Never mind that, on a yearly basis, COVID-19 kills about as many children as the measles did before the vaccine was licensed 60 years ago, adjusted for population?”

It was a comparison of deadliness, nothing more. Perhaps you should be working on your reading comprehension. Because your misinterpretation makes us question your medical competence (especially since you are not aware that cardiac issues are more common and worse with and actual Covid infection, not any of the several available vaccines).

“But T cell immunity seems to be far better from infection than vaccination.”

Are you sure about that, Jerry?

“The Pfizer/BioNTech mRNA vaccine directed at COVID-19 is much better than natural infection at revving up key immune cells called killer T cells to fight future infection by SARS-CoV-2, the virus that causes COVID-19, Stanford Medicine investigators have found.”

http://med.stanford.edu/news/all-news/2023/03/vaccine-covid-infection.html

Of course you do not any paper about T cell immunity, What data did CDC hie ? If antivaxxers are suppressed, how they are capable to generate so much noise ?

Quack Mixon ignores that DeSantis fired anyone in the Florida DPH that didn’t hide M & M data regarding COVID-19 infection. Florida did very poorly with COVID-19 infection.

Both the GBD and the “John Snow Declaration” represent wishes which, unfortunately, the Sars-Cov-2 virus did not grant.

GBD called for “obtaining natural immunity” and “protection of the vulnerable”. Guess what, the virus infected everyone, anyway, vulnerable or not.

John Snow declaration was wishing for “containing and eradicating”. Guess what, the virus infected everyone, anyway.

The vaccines made everything worse and instead of being “one and done”, now people get reinfected constantly. I know someone who had Covid (confirmed with positive tests) FIVE times. (yes, double vaxed)

I guess mixing HIV with sarbecoviruses was a really powerful idea.

We are now in the beginning of a very large wave of Covid (Europe is in the midst) caused by BA.2.86. Good luck and stay safe

I always value your comments, but that one is based on recorded cases, not total infections. There were ongoing efforts during the first couple years of the pandemic to gather blood samples and test for SARS-CoV-2 antibodies to get estimates of how many total people had been infected, not just the reported cases. I participated in one such survey, donating three finger-prick samples. I never quite figured out where the results were published.

Another way, which was used in this study, tested blood donations.
https://www.cdc.gov/mmwr/volumes/72/wr/mm7222a3.htm

They all have their uncertainties and limitations but for a while the estimates converged on a ratio of 3-4 infections per recorded case. I used a ratio of 3 for my calculations in an earlier comment.

That has undoubtedly gone down due to all the reinfections. And many people’s antibodies have all but disappeared, which further complicates such studies.

Here are a few quotes from that study.

By the third quarter of 2022 (July–September), 96.4% had SARS-CoV-2 antibodies from previous infection or vaccination, including 22.6% from infection alone and 26.1% from vaccination alone; 47.7% had hybrid immunity.
…..
During July–September 2022, the prevalence of infection-induced immunity was 85.7% (95% CI = 79.8%–90.2%) among unvaccinated persons and 64.3% (95% CI = 61.9%–66.7%) among vaccinated persons.
…..
Among persons with no previous infection, the incidence of first infections during the study period (i.e., conversion from anti-N–negative to anti-N–positive) was higher among unvaccinated persons (Table). From April–June 2021 through January–March 2022, the incidence of first SARS-CoV-2 infections among unvaccinated persons was 67.0%, compared with 26.3% among vaccinated persons (p<0.05). From January–March 2022 through April–June 2022, the incidence among unvaccinated persons was 21.7% and was 13.3% among vaccinated persons. Between April–June 2022 and July–September 2022, the incidence among unvaccinated persons was 28.3%, compared with 22.9% among vaccinated persons (p<0.05).

So vaccine protection even against just infection was pretty good before the Delta wave. Even during the height of the Omicron wave, you could still see a benefit. That benefit has declined but still shows up.

Which belies one person’s characterization of the vaccine as “equally worthless” !

That 96% of people with some protection has a lot to do with why deaths dropped from 58,000 in Jan 2022 to “only” 15,000 in Jan 2023.

Vaccines Save Lives!!!!

Keep in mind that a large fraction of vaccinated people do NOT seroconvert after a Covid infection and does not get the N antibodies. So looking at N antibodies is very useful amongst unvaccinated people, but gives biased results among vaccinated people.

In other words, some vaccinated people could have a confirmed Covid infection, and not develop N antibodies. So their N antibody prevalence may seem low, but it does NOT mean they escaped Covid.

@ Igor Chudov

First, give a valid reference regarding N antibodies. Second, our immune systems have both antibodies and a variety of t-cells; e.g., killer t-cells that kill viral infected cells, etc. And you continue to not understand in your immense stupidity that being infected doesn’t mean being sick, so not “escaping Covid” says nothing.

In addition to what Joel has replied, I would note that you are nit-picking about the details of the methodology used to generate what is acknowledged to be an estimate of the number of people infected. There are several factors that affect that estimate.

But you ignore the primary thrust of my comment, which was offered as a clarification to Aaron, but also as a supplement to my previous comment in response to a claim that the vaccines were “worthless.”

The large drop in the number of people who died of Covid-19 in the second winter compared to the first clearly shows the benefits of acquired immunity whether from infection or vaccination. And since many more people were vaccinated than infected at that time, it is clear that the vaccines had an important protective benefit.

I will review any published research you can find that might dispute my assessment, but I won’t be holding my breath.

For Joel’s benefit, I plan to read chapter 8 of Immune, by Phillip Dettmer. It’s not as detailed as Sompayrac, but is easy to read and gives a good overview of the immune system.

From the article
Both SARS-CoV-2 infection and COVID-19 vaccination result in production of anti-S antibodies, whereas anti-N antibodies only result from infection.
N antibodies were tested to estimate number of people who get antibodies solely from infection.

@ Igor Chudov

Being infected says very little. We are all infected with various viruses constantly; but our immune systems keep them in check. I prefer not to use anecdotes; but, for example, I am a 77 year old man. I walk my dog twice daily and often pass others on the sidewalk. I don’t wear a mask outdoors. I go shopping several times a month at grocery stores and have been to doctors office, dentist, and, of course, clinics to get vaccines. And do wear a mask when indoors. Yet, during the 3 years of the pandemic I have not even had the sniffles. And I have a good friend who is a kidney transplant patient and his wife is a type 1 diabetic and intensive care nurse. Neither have had COVID symptoms. I have spoken on phone with friends who live in other states, none have suffered symptoms of COVID; but certain they have been infected.

You just continue to display your stupid ignorance of infectious diseases and how our immune systems work. Being infected says nothing about most diseases as a healthy immune system keep them in check.

And you continue to display your absolute stupidity about vaccines. All vaccines do is create the absolutely same memory immune cells that an active infection creates. If we get sick, while suffering, takes 10 days for adaptive immune system to start working; e.g., antibodies. And at same time memory immune cells are created so that next time we get same infection they are already circulating and usually stop it cold. And no matter how many times this is explained to you, you will ignore it. So, not only are you totally ignorant about how our immune systems work; but stupidly dishonest in your continued assinine comments

“I guess mixing HIV with sarbecoviruses was a really powerful idea.”

“There is again this mixing HIV with coronavirus. So chrck HIV sequence and compare it with SARS CoV 2 sequence. No genes, just short sequences.”

I guess the education system and critical reading classes have let Igor down. This has been explained to him multiple times but he just can’t understand. A some point you have to realise that, no matter how hard you pump, that tyre just isn’t going to inflate.

I’ve been reading X posts** by people who have not studied medicine/ bio/ PH/ psych yet pontificate on those subjects:
I wonder if
their abysmal results reflect 1. a general lack of investigative skill because they leave out the most basic information and foundational research?***
As well as 2. problems with self criticism.

What set me off was reading the X of RFKjr who presents naive solutions to long standing international and national problems as if he is the first person to think of that!
Homelessness? Build millions of tiny homes! War in the Middle East? Bring peace! Childhood illness? Stop vaccines! Educational failure? His wife will fix that!

If you cannot see that you really have NOTHING and believe that all experts are wrong: you have serious problems.

Take Steve Kirsch. Or Naomi Wolf or any of the wan… commenters, who come here to argue with Orac et al:
they have little basic information yet repeat the same tropes and objections.
Hiv in Covid. Vaccines kill. PH measures destroyed society.

Wakefield famously avoided complex research which was well known about prenatal brain development when he crafted his infamous study.
yet anti-vaxxers label him a visionary.

The only way contrarians like these get attention is by blithely dismissing voluminous research accumulated over decades from all over the world.

to evade Elon, see nitter.net name/ handle
*** in contrast, Orac’s some of most astute commenters include engineers, software developers, physicists and
others not from the life sciences

“PH measures destroyed society.”

Well, if we’d just eat enough of the right foods to alkalinize our blood, there wouldn’t be any more societal upheaval.

It’s basic science.

@ Dr Bacon:

Despite your welcomed acid wit, isn’t it pH? Although alties would probably find a way work in green vegetables into any topic.

More seriously, Naomi Wolf ( Substack) recently submitted two masterpieces ( on Thanksgiving and rich people) that illustrate her uncanny ability to confabulate relationships between Covid measures and large scale societal trends and how people behave.
Just read for the full effect.

Hi Denice

Since you mentioned Wakefield, you might find an article I wrote about him of interest. Wrong About Vaccine Safety: A Review of Andrew Wakefield’s “Callous Disregard”. Open Vaccine Journal, 2013, 6, 9-25. Just cut and paste title in Google.

@ Joel, PhD, MPH:

Just wow.
You did a great job showing the depths of Wakefield’s oeuvre.
That was a lot of work.

I often venture that anti-vaxxers/ alties choose topics that are very complex and highly detailed so that they can easily pull the wool over their naive followers’ eyes and pretend expertise by citing numbers- often wrongly- and quoting studies. But if someone “goes into the weeds”, they point out the ruse(es).

It’s not “lack of investigative skill”, it’s lack of investigative ethics. If you know the answer before you begin researching it, you have to ignore the “most basic information and foundational research” because it’s all corrupted by Them (whoever They are). And it takes a certain ‘alternative’ investigative skill to find the material that confirms what you already know.

Not that confirmation bias never infects the work of more legitimate investigators, e. g. especially mainstream journalists. It’s just at an entirely different (lower) level, and much more subject to correction via public debates.

@ sadmar:

I do think that a few anti-vaxxers alties know that there is powerful – nearly unassailable- evidence that autism originates pre-natally, they just dismiss it because it contradicts their beliefs. In fact, it is rare that one of them even mentions it- Katie Wright once tried to say that a single study of the most quoted researcher was not relevant whilst assiduously ignoring the hundreds of other work that supports or elaborates it.

I used to list the names of these researchers but no longer do because anti-vaxxers are such great investigators, they can find them to refute easily themselves.
To give an idea of the complexity/ richness of this research, a lead scientist once gave a basic introductory lecture of over 2 hours with densely packed references and slides. It is mind boggling but every step in the process of discovery is confirmed and repeated.

It’s worth remembering that preferring post-infection (“natural”) immunity to vaccines only makes sense if you think it’s good for everyone to get sick at least once. Unfortunately, with covid neither vaccines nor “natural” infection provide lasting immunity–but at least my vaccine booster doesn’t put me at risk of long covid.

@ Igor Chudov

So, according to you they found no neutralizing antibodies; but, besides you giving no reference, there are other types of antibodies. Neutralizing antibodies attach to viruses and bacteria in solution; but other antibodies attach directly to, for instance, infected cells and macrophages then see them and kill the cells. And I could explain more; but i realize that you aren’t interested in actually learning anything about our immune systems.

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