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Bioethics Cancer Clinical trials Medicine Science Skepticism/critical thinking

Evidence-based medicine guidelines versus patient wishes

There’s a misconception that I frequently hear about evidence-based medicine (EBM), which can equally apply to science-based medicine (SBM). Actually, there are several, but they are related. These misconceptions include the idea that EBM/SBM guidelines are a straightjacket, that they are “cookbook medicine,” and that EBM/SBM should be the be-all and end-all of how to […]

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Clinical trials Complementary and alternative medicine Medicine Popular culture Science Skepticism/critical thinking

Better late than never: Orac comments on the hijacking of evidence-based medicine

It’s no secret that I’m a fan of John Ioannidis. (If you don’t believe me, just type Ioannidis’ name into the blog search box and see how many posts you find.) Over the last couple of decades, Ioannidis has arguably done more to reveal the shortcomings of the medical research enterprise that undergirds our treatments, […]

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Antivaccine nonsense Autism Complementary and alternative medicine Medicine Skepticism/critical thinking

Contrary to antivaccine claims, childhood immunization schedules are evidence-based

I write about vaccines a lot here at Respectful Insolence, and for a very good reason. Of all the medical interventions devised by the brains of humans, arguably vaccines have saved more lives and prevented more disability than any other medical treatment. When it comes to infectious disease, vaccination is the ultimate in preventive medicine, […]

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Clinical trials Medicine Science Skepticism/critical thinking

Choosing Wisely three years on

I like to point out from time to time that arguably the most striking difference between science-based medicine (and the evidence-based medicine from which we distinguish it) and alternative medicine, “complementary and alternative medicine” (CAM), or (as it’s called now) “integrative medicine” is a concerted effort to change practice for the better based on science […]

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Complementary and alternative medicine Medicine Quackery Science

The Nobel Prize versus traditional Chinese medicine

Last week, in response to the awarding of the Nobel Prize in Physiology or Medicine to Chinese scientist Youyou Tu, who isolated Artemisinin and validated it as a useful treatment for malaria back in the 1970s, I pointed out that the discovery was a triumph of natural products pharmacology, not of traditional Chinese medicine (TCM). […]