Cancer Clinical trials Science Skepticism/critical thinking

Precision medicine: Hype over hope?

I am fortunate to have become a physician in a time of great scientific progress. Back when I was in college and medical school, the thought that we would one day be able to sequence the human genome (and now sequence hundreds of cancer genomes), to measure the expression of every gene in the genome […]

Clinical trials Medicine Politics Popular culture Skepticism/critical thinking

The 21st Century Cures Act: Old vinegary wine in a new bottle

The approval of new drugs and medical devices is a process fraught with scientific, political, and ethical landmines. Inherent in any such process is an unavoidable conflict between rigorous science and safety on the one side, which tend to slow the process down by requiring large randomized clinical trials that can take years, versus forces […]

Biology Cancer Medicine Science

Is there gold in that thar genomic medicine?

I’ve written a lot about a doctor named Stanislaw Burzynski who claims to have much better outcomes in treating deadly brainstem tumors than conventional oncology does. Although the way he claims to do it is through the use of substances he calls “antineoplastons,” which he claimed to have isolate from the urine of patients. Over […]