Earlier this month, Chuck Norris and his wife Gena filed a lawsuit against manufacturers of MRI contrast agents, claiming that the gadolinium in them had “poisoned” Gena. But did it? The evidence linking gadolinium with the symptoms Gena Norris suffered is, even under the most generous interpretation, quite shaky, and there is no doubt that she has been victimized by quacks.
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Last week, the FDA released final regulatory guidance regarding freestanding stem cell clinics. The new regulatory framework appears custom-made to allow the FDA to crack down on quack stem cell clinics. But will it?
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Dr. David Brownstein is a “holistic” family practice physician in my area. Consistent with being “holistic,” he is antivaccine to the core. That’s why he’s unhappy with the recent CDC recommendation that adults over 50 receive the new shingles vaccine. He thinks he’s found a clever argument to show it doesn’t work. Unfortunately, his argument only reveals his bias and misunderstanding.
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Many are the antivaxers who claim they aren’t antivaccine. Few are the antivaxers who are honest enough to openly proclaim they are antivaccine.
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Last week, the results of ORBITA were published. This clinical trial tested coronary angioplasty and stenting versus optimal medical management in patients with single-vessel coronary artery disease. It was a resoundingly negative trial, meaning that adding stenting to drug management didn’t result in detectable clinical improvement. What was distinctive about this trial is that it used a sham procedure (i.e., placebo) control, which few trials testing surgery or a procedure use. The results of ORBITA emphasize how important sham procedure controls are, whenever they can be ethically used, and how resistant physicians can be to change.
