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Biology Cancer Clinical trials Medicine Pseudoscience Skepticism/critical thinking

Is there a reproducibility "crisis" in biomedical research?

Most scientists I know get a chuckle out of the Journal of Irreproducible Results (JIR), a humor journal that often parodies scientific papers. Back in the day, we used to chuckle at articles like “Any Eye for an Eye for an Arm and a Leg: Applied Dysfunctional Measurement” and “A Double Blind Efficacy Trial of […]

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Antivaccine nonsense Biology Cancer Clinical trials Complementary and alternative medicine Medicine Science Skepticism/critical thinking

John Oliver teaches us how to interpret medical and scientific studies

It’s no secret that I’m a big fan of John Oliver. When my aging body allows me to stay awake late enough on Sunday nights and there’s a new episode on, I’ll almost always be watching. Since starting his own show Last Week Tonight With John Oliver on HBO, Oliver’s become quite the expert at […]

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Clinical trials Complementary and alternative medicine Medicine Popular culture Science Skepticism/critical thinking

Better late than never: Orac comments on the hijacking of evidence-based medicine

It’s no secret that I’m a fan of John Ioannidis. (If you don’t believe me, just type Ioannidis’ name into the blog search box and see how many posts you find.) Over the last couple of decades, Ioannidis has arguably done more to reveal the shortcomings of the medical research enterprise that undergirds our treatments, […]

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Clinical trials Medicine Science Skepticism/critical thinking

Fixing peer review

I’ve frequently noted that one of the things most detested by quacks and promoters of pseudoscience is peer review. Creationists hate peer review. HIV/AIDS denialists hate it. Anti-vaccine cranks like those at Age of Autism hate it. Indeed, as blog bud Mark Hoofnagle Mark Hoofnagle, pointed out several years ago, pseudoscientists and cranks of all […]

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Antivaccine nonsense Complementary and alternative medicine Medicine Quackery Science Skepticism/critical thinking

The Triumph of New Age Medicine, part deux, courtesy of The Atlantic

There can be no doubt that, when it comes to medicine, The Atlantic has an enormous blind spot. Under the guise of being seemingly “skeptical,” the magazine has, over the last few years, published some truly atrocious articles about medicine. I first noticed this during the H1N1 pandemic, when The Atlantic published an article lionizing […]