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Biology Cancer Medicine Science Skepticism/critical thinking

No, the PSA test probably didn’t save Ben Stiller’s life

A frequent topic of discussion on this blog is the concept of overdiagnosis. It’s a topic I’ve been writing about regularly since around 2007 or so and is defined as the detection in an asymptomatic person of disease that, if left alone, would never progress to endanger that person’s life or well-being within his or […]

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Cancer Complementary and alternative medicine Medicine Quackery Skepticism/critical thinking

Sayer Ji: Willfully misunderstanding overdiagnosis and misdiagnosis since…forever

If there’s one lesson that I like to emphasize while laying down my near-daily dose of Insolence, both Respectful and not-so-Respectful, it’s that practicing medicine and surgery is complicated. Part of the reason that it’s complicated is that for many diseases our understanding is incomplete, meaning that physicians have to apply existing science to their […]

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Antivaccine nonsense Autism Popular culture Pseudoscience

Autism prevalence increases, and antivaxers blame it on vaccines (2018 edition)

As it does every two years, the CDC has issued its 2018 report on autism prevalence. As in years past, autism prevalence has ticked upward. As in years past, antivaxers have tried to blame it on vaccines. As in years past, they’re wrong. Vaccines are not responsible for increased autism prevalence.

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Medicine

How overdiagnosis produced a nonexistent “epidemic” of thyroid cancer in Fukushima

One of my favorite topics to blog about over the last six or seven years has been the topic of overdiagnosis and overtreatment. These are two interrelated phenomena that most people are blissfully unaware of. Unfortunately, I’d also say that the majority of physicians are only marginally more aware than the public about these confounders […]

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Biology Cancer Computers and social media Medicine Skepticism/critical thinking

Microsoft vows to “solve cancer” in a decade. Hubris ensues.

If there’s one thing that irritates me more than government agencies making bold proclamations about making progress in cancer but not providing sufficient funding to have even a shot of realizing such ambitions (I’m talking to you, Cancer Moonshot), it’s people in other disciplines that are not cancer biology making bold proclamations about how they’re […]