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Biology Cancer Clinical trials Medicine Science Skepticism/critical thinking

A study of overdiagnosis due to mammography reported during Breast Cancer Awareness Month

I knew it. I just knew it. I knew I couldn’t get through October, a.k.a. Breast Cancer Awareness Month, without a controversial mammography study to sink my teeth into. And I didn’t. I suppose I should just be used to this now. I’m referring to the latest opus from H. Gilbert Welch and colleagues that […]

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Cancer Complementary and alternative medicine Medicine Quackery Skepticism/critical thinking

Sayer Ji: Willfully misunderstanding overdiagnosis and misdiagnosis since…forever

If there’s one lesson that I like to emphasize while laying down my near-daily dose of Insolence, both Respectful and not-so-Respectful, it’s that practicing medicine and surgery is complicated. Part of the reason that it’s complicated is that for many diseases our understanding is incomplete, meaning that physicians have to apply existing science to their […]

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Medicine

How overdiagnosis produced a nonexistent “epidemic” of thyroid cancer in Fukushima

One of my favorite topics to blog about over the last six or seven years has been the topic of overdiagnosis and overtreatment. These are two interrelated phenomena that most people are blissfully unaware of. Unfortunately, I’d also say that the majority of physicians are only marginally more aware than the public about these confounders […]

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Cancer Clinical trials Medicine

The Canadian Breast Screening Study attacked: Why do doctors have such a hard time with the concept of overdiagnosis?

The last couple of weeks, I’ve made allusions to the “Bat Signal” (or, as I called it, the “Cancer Signal,” although that’s a horrible name and I need to think of a better one). Basically, when Bat Cancer Signal goes up (hey, I like that one better, but do bats get cancer?), it means that […]

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Cancer Medicine

Cancer overdiagnosis and overtreatment revisited

I think the message may finally getting through. That message is that it’s not always the best strategy to treat cancer aggressively. Don’t get me wrong. If I have acute leukemia, I know I’ll need the big guns, every bit of chemotherapy appropriate to the disease that modern oncology can throw at it up to […]