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Cancer Clinical trials Medicine

The mammography wars heat up again

Unfortunately, it’s grant application crunch time again over the weekend. That means something’s got to give, and what happened to be the thing to give was this blog. Fortunately, all is not lost, as a “good friend” of mine has commented on a recent New England Journal of Medicine study from Thursday about mammography. It […]

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Complementary and alternative medicine Friday Woo Medicine Quackery Skepticism/critical thinking

Your Friday Dose of Woo: Activate your DNA!

Every so often, real life intrudes on blogging, preventing the creation of fresh Insolence, at least Insolence of the quality that you’ve come to expect. This is one of those times. Besides getting into full R01 grant-writing swing, I went out to dinner last night with a visiting professor and didn’t get home until too […]

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Complementary and alternative medicine Homeopathy Medicine Naturopathy Quackery

A highly revealing quote from a naturopath

Naturopathy is a strange beast in the “alternative medicine” world. From what I’ve been able to tell, it’s a wastebasket specialty with no overarching philosophical underpinnings, as traditional Chinese medicine underpins acupuncture or sympathetic magic underpins homeopathy. Basically, if it’s woo, naturopaths will use it. Acupuncture, TCM, homeopathy, herbalism, nutritional woo, detox, it doesn’t matter. […]

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Complementary and alternative medicine Entertainment/culture Humor Medicine Music Popular culture Religion

Quoth über-quack Mike Adams: Beware Lady Gaga. She worships…death!

I’ve expounded on the principle of crank magnetism. Basically, crank magnetism is the tendency of cranks not to mind the crankery of other cranks, even if the two forms of crankery are mutually exclusive. But it’s more than that. It’s the tendency of a single crank to be attracted to several forms of crankery. We’ve […]

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Bioethics Cancer Clinical trials Medicine Science

Balancing scientific rigor versus patient good in clinical trials

A critical aspect of both evidence-based medicine (EBM) and science-based medicine (SBM) is the randomized clinical trial. Ideally, particularly for conditions with a large subjective component in symptomatology, the trial should be randomized, double-blind, and placebo-controlled. As Kimball Atwood pointed out just last week (me too), in EBM, scientific prior probability tends to be discounted […]