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Antivaccine nonsense Medicine

Pertussis outbreaks and vaccine effectiveness

About a month ago, I deconstructed a typically dishonest and deceitful attempt by that Overlord of Quackery on the Internet (in my opinion, of course), Joe Mercola, to claim that the acellular pertussis vaccine doesn’t work. It was a typical Mercola bit of prestidigitation that, as so much antivaccine propaganda does, took a grain of […]

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Cancer Clinical trials Medicine Surgery

On the enormous variability of cancer behavior

Perhaps one of the most common misconceptions held about cancer among lay people is that it is one disease. We often hear non-physicians talk about “curing cancer” as though it were a single disease. Sometimes, we even hear physicians, who should know better, using the same sort of fuzzy thinking and language about “curing cancer” […]

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Cancer Clinical trials Complementary and alternative medicine Medicine Surgery

The spontaneous regression of breast cancer?

I tell ya, I’m on the light blogging schedule for a mere four days, thanks to the Thanksgiving holiday weekend, the happy invasion of family on Thursday and Friday, and a significant amount of grant writing I’ve had to deal with on Saturday and Sunday, and somehow I missed not only a study relevant to […]

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Complementary and alternative medicine Medicine Science Skepticism/critical thinking

Knowledge versus certainty in skepticism, medicine, and science

“I don’t want knowledge. I want certainty!” –David Bowie, from Law (Earthlings on Fire) If there’s one universal trait among humans, it seems to be an unquenchable thirst for certainty. This should come as no surprise to those committed to science and rational thinking because there is a profound conflict between our human desire for […]

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Cancer Medicine

Cancer overdiagnosis and overtreatment revisited

I think the message may finally getting through. That message is that it’s not always the best strategy to treat cancer aggressively. Don’t get me wrong. If I have acute leukemia, I know I’ll need the big guns, every bit of chemotherapy appropriate to the disease that modern oncology can throw at it up to […]