There are times when, as a scientist, I look at an idea and its execution and simply stand in awe. It’s particularly satisfying when it’s a relatively simple idea that could conceivably do a lot of good for a lot of patients. Oddly enough, whether it’s because I’ve been out of the loop or because […]
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Be careful what you ask for; you just might get it. I say this in light of a commenter, who decided to show up in one of my old posts to claim “positive results” from dichloroacetate (DCA), the small molecule experimental cancer drug that has shown promising activity in rat models of cancer but has […]
I hadn’t planned on revisiting this topic again quite so soon, but sometimes a piece of information comes up that’s so disturbing that I can’t ignore it and can’t justify delaying blogging about it by very long. So it is yet again with the strange and disturbing saga of dichloroacetate (DCA), the small molecular chemotherapeutic […]
It never seems to end, does it? I’m talking about the hype and questionable practices revolving around dichloroacetate (DCA), the small molecule chemotherapeutic agent that targets the Warburg effect, in essence normalizing the metabolism of tumor cells and thereby inhibiting their growth. (See here and here for more details.) A report by Evangelos Michelakis at […]
I love it. You see I noticed an old “friend,” the Herbinator, making this comment about me regarding dichloroacetate: I was listening to CBC Radio – the Current, as is my want, and there was a show on about DCA, or Dichloroacetic acid. DCA is a molecule so simple and cheap to make that drug […]