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Clinical trials Medicine Science

Things like this make medical science worthwhile: A drug to treat genetic diseases due to nonsense mutations

There are times when, as a scientist, I look at an idea and its execution and simply stand in awe. It’s particularly satisfying when it’s a relatively simple idea that could conceivably do a lot of good for a lot of patients. Oddly enough, whether it’s because I’ve been out of the loop or because […]

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Bioethics Cancer Clinical trials Medicine Politics

Dichloroacetate and The DCA Site: A low bar for “success” (part 2)

Be careful what you ask for; you just might get it. I say this in light of a commenter, who decided to show up in one of my old posts to claim “positive results” from dichloroacetate (DCA), the small molecule experimental cancer drug that has shown promising activity in rat models of cancer but has […]

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Bioethics Cancer Clinical trials Medicine Quackery Skepticism/critical thinking

“Clinical research” on dichloroacetate by TheDCASite.com: A travesty of science

I hadn’t planned on revisiting this topic again quite so soon, but sometimes a piece of information comes up that’s so disturbing that I can’t ignore it and can’t justify delaying blogging about it by very long. So it is yet again with the strange and disturbing saga of dichloroacetate (DCA), the small molecular chemotherapeutic […]

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Bioethics Cancer Clinical trials Medicine

A family practitioner and epidemiologist are prescribing dichloracetate (DCA) in Canada

It never seems to end, does it? I’m talking about the hype and questionable practices revolving around dichloroacetate (DCA), the small molecule chemotherapeutic agent that targets the Warburg effect, in essence normalizing the metabolism of tumor cells and thereby inhibiting their growth. (See here and here for more details.) A report by Evangelos Michelakis at […]

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Bioethics Cancer Clinical trials Complementary and alternative medicine Medicine Quackery

An “arrogant medico” makes one last comment on dichloroacetate (DCA)

I love it. You see I noticed an old “friend,” the Herbinator, making this comment about me regarding dichloroacetate: I was listening to CBC Radio – the Current, as is my want, and there was a show on about DCA, or Dichloroacetic acid. DCA is a molecule so simple and cheap to make that drug […]