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Biology Cancer Clinical trials Evolution Medicine Science

The Human Genome Project: Hype meets reality

I’ve had the immense good fortune to have trained and ultimately become a physician-scientist during a time when the pace of discovery and the paradigm changes in science have occurred just over the course of my career in medicine and science has been staggering. microRNA, the shift from single gene studies to genomics, the development […]

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Biology Clinical trials Evolution Medicine Physics Science Skepticism/critical thinking

Is the “decline effect” really so mysterious?

NOTE: Orac was actually out rather late last night. It turns out that the more administrative responsibility he somehow seems to find the more he has to go out to dinner as a part of various cancer center-related functions. As a result, he is recycling a bit of recent material from elsewhere that he in […]