I’m a cancer surgeon. I started out as a general surgeon, but my passion and scientific interest goaded me into specializing in cancer. Ultimately, I ended up subspecializing even more, ultimately becoming a breast cancer surgeon, but through it all cancer, not just breast cancer, has remained my clinical and scientific passion. So has science-based […]
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A critical aspect of both evidence-based medicine (EBM) and science-based medicine (SBM) is the randomized clinical trial. Ideally, particularly for conditions with a large subjective component in symptomatology, the trial should be randomized, double-blind, and placebo-controlled. As Kimball Atwood pointed out just last week (me too), in EBM, scientific prior probability tends to be discounted […]
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If there’s one thing that burns me about so-called “complementary and alternative medicine” (CAM) clinical trials, it’s how unethical many of them are. This is particularly true for trials that test modalities that, on the basic science grounds alone, can be dismissed as so highly implausible and with such a low prior probability of success […]
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The Lorne Trottier Symposium is over, and it went quite well. Amazingly, even though I had to follow Michael Shermer’s talk, people told me I didn’t suck, which made me feel better. Oh, there was this issue of a guy who wanted to tout Royal Rife and his machine. He wouldn’t have irritated me so […]
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Over my nearly six years of blogging, I’ve become known as a staunch advocate of science- and evidence-based medicine, both in the guise going under my long-used pseudonym “Orac” and under my real name. And so I am, which is why certain varieties of predictable attacks on science-based medicine (SBM) annoy me. Usually, they come […]
