After chilling out for part of the weekend, yesterday I became so engrossed in writing my part of a training grant for my postdoc that, before I knew it, it was way too late to provide you with the Insolence you crave for today. Oh, well. Tomorrow for sure; there’s a lot that has been […]
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Here and elsewhere in the blogosphere, over the last several years, what started out as a more general interest in skepticism and science with a natural focus on medicine and a side interest in combatting Holocaust denial became more focused on promoting science-based medicine. As the saying goes, “Science, it works, bitches,” and I make […]
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Regarding this whole skeptic thing, if there’s one thing I’ve learned about pseudoscience and bizarre, unscientific beliefs, it’s that, just when I think I’ve seen it all, the world slaps me in the face (facepalm, to be precise) to show me that I haven’t seen it all after all. Such was what happened when a […]
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A critical aspect of both evidence-based medicine (EBM) and science-based medicine (SBM) is the randomized clinical trial. Ideally, particularly for conditions with a large subjective component in symptomatology, the trial should be randomized, double-blind, and placebo-controlled. As Kimball Atwood pointed out just last week (me too), in EBM, scientific prior probability tends to be discounted […]
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Way, way back in the deepest darkest depths of history, before I entered the Knowledge Room and sold my soul to big pharma to become a pharma blogger (in other words, way back in 2005), my inauguration as a skeptical blogger taking on anti-vaccine misinformation, pseudoscience, and lies occurred in a big way when I […]
