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Biology Cancer Clinical trials Medicine

NIH funding: The dreaded issue of conformity rears its ugly head again

For all the worship of “translational” research that is currently in vogue, it needs to be remembered that a robust pipeline of basic science progress upon which to base translational research and clinical trials is absolutely essential if progress in medicine is to continue. Without it, progress in SBM will slow and even grind to […]

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Antivaccine nonsense Autism Complementary and alternative medicine

A simultaneously sympathetic and unsympathetic commentary on an antivaccine screed

The false idea that vaccines somehow cause or contribute to autism has been a common theme on this blog, and I’ve spent considerable verbiage discussing why anyone would think that vaccines are in any way associated with autism when the science is quite clear that they are not. If there’s one thing I’ve been consistent […]

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Medicine Politics

Big pharma wins a battle on off-label prescribing

There’s a phenomenon known as off-label prescribing. Basically, to prescribe something off-label is to prescribe it for an indication that is not FDA-approved but that is supported by considerable evidence. For example, it could involve using an FDA-approved drug for an indication that is not within its approval, for an unapproved age range (such as […]

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Cancer Complementary and alternative medicine Quackery

Stanislaw Burzynski: On the arrogance of ignorance about cancer and targeted therapies

Here we go again. Because he’s been in the news lately, I’ve been writing a lot about the “brave maverick doctor” known as Stanislaw Burzynski who claims to have spectacular results treating normally incurable cancers using something he calls antineoplastons. Unfortunately, the reason Burzynski has featured prominently in the skeptical blogosphere over the last two […]

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Antivaccine nonsense Complementary and alternative medicine Quackery

The mummer’s farce that was the Congressional autism hearing last week

Last Wednesday, I took note of an “old friend” and (thankfully) soon-to-be ex-Representative from Indiana’s 5th Congressional District, organized quackery’s best friend in the U.S. House of Representatives, Dan Burton. Specifically, I noted that Rep. Burton appeared to be having his one last antivaccine hurrah in the form of a hearing about the “autism epidemic” […]