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Biology Cancer Clinical trials Medicine Science Skepticism/critical thinking

A study of overdiagnosis due to mammography reported during Breast Cancer Awareness Month

I knew it. I just knew it. I knew I couldn’t get through October, a.k.a. Breast Cancer Awareness Month, without a controversial mammography study to sink my teeth into. And I didn’t. I suppose I should just be used to this now. I’m referring to the latest opus from H. Gilbert Welch and colleagues that […]

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Bioethics Cancer Clinical trials Medicine Science Skepticism/critical thinking

Evidence-based medicine guidelines versus patient wishes

There’s a misconception that I frequently hear about evidence-based medicine (EBM), which can equally apply to science-based medicine (SBM). Actually, there are several, but they are related. These misconceptions include the idea that EBM/SBM guidelines are a straightjacket, that they are “cookbook medicine,” and that EBM/SBM should be the be-all and end-all of how to […]

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Biology Cancer Medicine Science Skepticism/critical thinking

No, the PSA test probably didn’t save Ben Stiller’s life

A frequent topic of discussion on this blog is the concept of overdiagnosis. It’s a topic I’ve been writing about regularly since around 2007 or so and is defined as the detection in an asymptomatic person of disease that, if left alone, would never progress to endanger that person’s life or well-being within his or […]

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Biology Cancer Computers and social media Medicine Skepticism/critical thinking

Microsoft vows to “solve cancer” in a decade. Hubris ensues.

If there’s one thing that irritates me more than government agencies making bold proclamations about making progress in cancer but not providing sufficient funding to have even a shot of realizing such ambitions (I’m talking to you, Cancer Moonshot), it’s people in other disciplines that are not cancer biology making bold proclamations about how they’re […]

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Biology Cancer Medicine Politics

Can the Cancer Moonshot do what its advocates promise?

The Cancer Moonshot. It’s a topic that I’ve been meaning to address ever since President Barack Obama announced it in his State of the Union address this year and tasked Vice President Joe Biden to head up the initiative. Biden, you’ll recall, lost his son to a brain tumor . Yet here it is, eight […]