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Biology Cancer Clinical trials Medicine Science Skepticism/critical thinking

A study of overdiagnosis due to mammography reported during Breast Cancer Awareness Month

I knew it. I just knew it. I knew I couldn’t get through October, a.k.a. Breast Cancer Awareness Month, without a controversial mammography study to sink my teeth into. And I didn’t. I suppose I should just be used to this now. I’m referring to the latest opus from H. Gilbert Welch and colleagues that […]

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Cancer Medicine Politics

Overdiagnosis of breast cancer due to mammography

Screening for disease, especially cancer, is a real bitch. I was reminded of this by the publication of a study in BMJ the very day of the Science-Based Medicine Conference a week and a half ago. Unfortunately, between The Amaz!ng Meeting and other activities, I was too busy to give this study the attention it […]

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Cancer Complementary and alternative medicine Medicine Quackery Skepticism/critical thinking

Sayer Ji: Willfully misunderstanding overdiagnosis and misdiagnosis since…forever

If there’s one lesson that I like to emphasize while laying down my near-daily dose of Insolence, both Respectful and not-so-Respectful, it’s that practicing medicine and surgery is complicated. Part of the reason that it’s complicated is that for many diseases our understanding is incomplete, meaning that physicians have to apply existing science to their […]

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Medicine

How overdiagnosis produced a nonexistent “epidemic” of thyroid cancer in Fukushima

One of my favorite topics to blog about over the last six or seven years has been the topic of overdiagnosis and overtreatment. These are two interrelated phenomena that most people are blissfully unaware of. Unfortunately, I’d also say that the majority of physicians are only marginally more aware than the public about these confounders […]

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Cancer Clinical trials Medicine

Once more into the breach: The American Cancer Society publishes new mammography guidelines

One of the things that feels the weirdest about having done the same job, having been in the same specialty, for a longer and longer time is that you frequently feel, as the late, great Yogi Berra would have put it, déjà vu all over again. This is particularly true in science and medicine, where […]