A critical aspect of both evidence-based medicine (EBM) and science-based medicine (SBM) is the randomized clinical trial. Ideally, particularly for conditions with a large subjective component in symptomatology, the trial should be randomized, double-blind, and placebo-controlled. As Kimball Atwood pointed out just last week (me too), in EBM, scientific prior probability tends to be discounted […]
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THE PAST IS PROLOGUE Location: Central New Jersey, deep within the brick and steel of a secret pharma base. Year: 1999. A shadowy figure dressed in gray, bald, and stroking a white cat enters a nondescript room in the middle of which sits a massive conference table. More than a dozen men and women leap […]
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Having followed the anti-vaccine movement continuously for nearly six years now, I had come to think that I had seen it all as far as deceptive strategies for frightening parents about vaccines. Obviously, becoming too complacent is foolish, because, as misguided and scientifically ignorant as they are, many of the leaders of the anti-vaccine movement […]
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One of the main topics that I’ve covered over the last four or five of laying down a swath of not-so-Respectful Insolence directed at pseudoscience is the relatively rapid, seemingly relentless infiltration of pseudoscience into what should be bastions of science-based medicine (SBM), namely medical schools and academic medical centers promoted by academics who should, […]
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Having spent the last couple of days dealing with pure woo, such as germ theory denialism and naturopathic quackery, I think now’s as good a time as any to move on to a more serious topic. One of the most important aspects of science is the publication of scientific results in peer-reviewed journals. This publication […]
