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Clinical trials Medicine Science Skepticism/critical thinking

Choosing Wisely three years on

I like to point out from time to time that arguably the most striking difference between science-based medicine (and the evidence-based medicine from which we distinguish it) and alternative medicine, “complementary and alternative medicine” (CAM), or (as it’s called now) “integrative medicine” is a concerted effort to change practice for the better based on science […]

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Cancer Clinical trials Medicine

Once more into the breach: The American Cancer Society publishes new mammography guidelines

One of the things that feels the weirdest about having done the same job, having been in the same specialty, for a longer and longer time is that you frequently feel, as the late, great Yogi Berra would have put it, déjà vu all over again. This is particularly true in science and medicine, where […]

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Cancer Clinical trials Medicine Politics Popular culture Science Skepticism/critical thinking

Governor Jerry Brown protects patients by vetoing California’s right-to-try bill

When last I discussed the cruel sham that is the tide of “right-to-try” laws that has been flowing through state legislatures to become law over the last year and a half. “Right-to-try” laws, as I pointed out when I first noted the earliest ones being promoted in Colorado, Louisiana, Arizona, and Missouri, referring to them […]

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Biology Clinical trials Complementary and alternative medicine Medicine Science

The 2015 Nobel Prize in Physiology or Medicine for the discoverer of Artemisinin: A triumph of natural product pharmacology, not traditional Chinese medicine

Earlier this week, the Nobel Prize in Physiology or Medicine was awarded to Youyou Tu for her discovery of the anti-malaria compound Artemisinin, as well as to William C. Campbell and Satoshi Ōmura for their discovery of a novel therapy for roundworm. Artemisinin, as some of you might know, is a compound derived from traditional […]

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Biology Cancer Clinical trials Popular culture

“Liquid biopsies” for cancer: not ready for prime time

I’ve written many times about how the relationship between the early detection of cancer and decreased mortality from cancer is not nearly as straightforward as the average person—even the average doctor—thinks, the first time being in the very first year of this blog’s existence. Since then, the complexities and overpromising of various screening modalities designed […]